RAB11FIP4

The protein encoded by this gene interacts with RAB11 and is thought to be involved in bringing recycling endosome membranes to the cleavage furrow in late cytokinesis. Hypoxic conditions can lead to an upregulation of the encoded protein and enhance the metastatic potential of hepatocellular carcinoma. [provided by RefSeq, Oct 2016]

Full Name

RAB11 Family Interacting Protein 4

Function

Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6.

Biological Process

Biological Process endocytic recyclingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of cytokinesisManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

Endosome
Cytoplasm, cytoskeleton, spindle
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Recycling endosome membrane
Cleavage furrow
Midbody
Cytoplasmic vesicle
Recruited to the cleavage furrow and the midbody during cytokinesis.

Anti-RAB11FIP4 antibodies

Mouse Anti-RAB11FIP4 Recombinant Antibody (13B5) (CBMAB-R0701-CN)

Datasheet

SDS

Target: RAB11FIP4

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 13B5

Application*: WB, IH

Mouse Anti-RAB11FIP4 Recombinant Antibody (4C9) (CBMAB-R0702-CN)

Datasheet

SDS

Target: RAB11FIP4

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 4C9

Application*: WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)