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Mouse Anti-RAB11FIP4 Recombinant Antibody (4C9) (CBMAB-R0702-CN)

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Datasheet
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Basic Information

Host Animal
Mouse
Clone
4C9
Application
WB
Immunogen
Human recombinant protein fragment corresponding to aa. 91-177 of human RAB11FIP4 (NP_116321) produced in E.coli
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.3, 1% BSA, 50% Glycerol
Preservative
0.02% Sodium azide
Concentration
1 mg/mL
More Infomation

Target

Full Name
RAB11 Family Interacting Protein 4
Introduction
The protein encoded by this gene interacts with RAB11 and is thought to be involved in bringing recycling endosome membranes to the cleavage furrow in late cytokinesis. Hypoxic conditions can lead to an upregulation of the encoded protein and enhance the metastatic potential of hepatocellular carcinoma. [provided by RefSeq, Oct 2016]
Entrez Gene ID
84440
UniProt ID
Q86YS3
Alternative Names
RAB11 Family Interacting Protein 4; RAB11 Family Interacting Protein 4 (Class II); Arfophilin-2; RAB11-FIP4; FIP4-Rab11; Rab11 Family-Interacting Protein 4; KIAA1821; ARFO2;
Function
Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6.
Biological Process
Biological Process endocytic recyclingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of cytokinesisManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Endosome
Cytoplasm, cytoskeleton, spindle
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Recycling endosome membrane
Cleavage furrow
Midbody
Cytoplasmic vesicle
Recruited to the cleavage furrow and the midbody during cytokinesis.
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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-RAB11FIP4 Recombinant Antibody (13B5) (CAT#: CBMAB-R0701-CN)

Isotype control

For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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