RAB5C

Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]). [supplied by OMIM, Nov 2010]
Full Name
RAB5C, Member RAS Oncogene Family
Function
Protein transport. Probably involved in vesicular traffic.
Biological Process
Biological Process endocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process plasma membrane to endosome transportManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process regulation of endocytosisManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cell membrane
Early endosome membrane
Melanosome
Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
PTM
Phosphorylation of Ser-85 in the switch II region by LRRK2 prevents the association of RAB regulatory proteins, including CHM, CHML and RAB GDP dissociation inhibitors GDI1 and GDI2.
(Microbial infection) Glycosylated on arginine residues by S.typhimurium protein Ssek3.
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Anti-RAB5C antibodies

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Mouse Anti-RAB5C Recombinant Antibody (16C222) (CBMAB-R0922-CN)

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Target: RAB5C
Host: Mouse
Specificity: Human
Clone: 16C222
Application*: E, WB
Datasheet SDS

Mouse Anti-RAB5C Recombinant Antibody (1616CT314.65.31) (CBMAB-R0921-CN)

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Target: RAB5C
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1616CT314.65.31
Application*: WB
Datasheet SDS

Rabbit Anti-RAB5C Recombinant Antibody (CBCNR-061) (CBMAB-R0018-CN)

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Target: RAB5C
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBCNR-061
Application*: WB, P, IF
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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