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Rabbit Anti-RAB5C Recombinant Antibody (CBCNR-061) (CBMAB-R0018-CN)

This product is a Rabbit antibody that recognizes RAB5C. The antibody CBCNR-061 can be used for immunoassay techniques such as: WB, IHC-P, IF.
See all RAB5C antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBCNR-061
Antibody Isotype
IgG
Application
WB, IHC-P, IF

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
RAB5C, Member RAS Oncogene Family
Introduction
Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]). [supplied by OMIM, Nov 2010]
Entrez Gene ID
5878
UniProt ID
P51148
Alternative Names
RAB5C, Member RAS Oncogene Family; RAB5C, Member Of RAS Oncogene Family; L1880; RAB5L; RABL; RAB, Member Of RAS Oncogene Family-Like; Ras-Related Protein Rab-5C; RAB5CL;
Function
Protein transport. Probably involved in vesicular traffic.
Biological Process
Biological Process endocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process plasma membrane to endosome transportManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process regulation of endocytosisManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cell membrane
Early endosome membrane
Melanosome
Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
PTM
Phosphorylation of Ser-85 in the switch II region by LRRK2 prevents the association of RAB regulatory proteins, including CHM, CHML and RAB GDP dissociation inhibitors GDI1 and GDI2.
(Microbial infection) Glycosylated on arginine residues by S.typhimurium protein Ssek3.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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