Mouse Anti-RAB5C Recombinant Antibody (1616CT314.65.31) (CBMAB-R0921-CN)

Name: Mouse Anti-RAB5C Recombinant Antibody (1616CT314.65.31)
SKU: CBMAB-R0921-CN
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

1616CT314.65.31

Application

Immunogen

A recombinant protein of human RAB5C

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

More Infomation

Target

Full Name

RAB5C, Member RAS Oncogene Family

Introduction

Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]). [supplied by OMIM, Nov 2010]

Entrez Gene ID

5878

UniProt ID

P51148

Alternative Names

RAB5C, Member RAS Oncogene Family; RAB5C, Member Of RAS Oncogene Family; L1880; RAB5L; RABL; RAB, Member Of RAS Oncogene Family-Like; Ras-Related Protein Rab-5C; RAB5CL;

Function

Protein transport. Probably involved in vesicular traffic.

Biological Process

Biological Process endocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process plasma membrane to endosome transportManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process regulation of endocytosisManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cell membrane
Early endosome membrane
Melanosome
Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

PTM

Phosphorylation of Ser-85 in the switch II region by LRRK2 prevents the association of RAB regulatory proteins, including CHM, CHML and RAB GDP dissociation inhibitors GDI1 and GDI2.
(Microbial infection) Glycosylated on arginine residues by S.typhimurium protein Ssek3.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Mouse Anti-RAB5C Recombinant Antibody (16C222) (CAT#: CBMAB-R0922-CN)

Rabbit Anti-RAB5C Recombinant Antibody (CBCNR-061) (CAT#: CBMAB-R0018-CN)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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