RAET1E
Members of the RAET1 family, such as RAET1E, are major histocompatibility complex (MHC) class I-related genes located within a 180-kb cluster on chromosome 6q24.2-q25.3. RAET1 proteins contain MHC class I-like alpha-1 and alpha-2 domains. RAET1E and RAET1G (MIM 609244) differ from the other RAET1 proteins (e.g., RAET1I, or ULBP1; MIM 605697) in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. (Radosavljevic et al., 2002 [PubMed 11827464]).[supplied by OMIM
Full Name
retinoic acid early transcript 1E
Function
Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
Biological Process
Biological Process natural killer cell mediated cytotoxicityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of natural killer cell mediated cytotoxicityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of natural killer cell mediated cytotoxicityManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Membrane
Isoform 4
Secreted
Isoform 4
Secreted
Topology
Extracellular: 31-225
Helical: 226-248
Cytoplasmic: 249-263
Helical: 226-248
Cytoplasmic: 249-263
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Anti-RAET1E antibodies
+ Filters

Target: RAET1E
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2D11
Application*: E
Target: RAET1E
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 79/6
Application*: E, F, IF, IP, FN, WB
Target: RAET1E
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 79/6/13/16
Application*: WB, IP, E, N, FC, IF
Target: RAET1E
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: RAET1E 79/6
Application*: FC
Target: RAET1E
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: RAET1E 119/6
Application*: FC
Target: RAET1E
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 709116
Application*: FC
Target: RAET1E
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBWJN-1650
Application*: F, P, WB
Target: RAET1E
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBWJN-1649
Application*: F, N
Target: RAET1E
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 50/3
Application*: E, F, IF, IP, N, WB
Target: RAET1E
Host: Rat
Specificity: Mouse
Clone: 15H135
Application*: F, N
Target: RAET1E
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 119/6
Application*: E, F, IF, IP, N, WB
Target: RAET1E
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 205001
Application*: F, N, MC
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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