RBM3

This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have been characterized although some of these variants fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq]
Full Name
RNA binding motif (RNP1, RRM) protein 3
Function
Cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. Reduces the relative abundance of microRNAs, when overexpressed. Enhances phosphorylation of translation initiation factors and active polysome formation (By similarity).
Biological Process
Biological Process positive regulation of mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of translationISS:UniProtKB
Biological Process regulation of translationISS:UniProtKB
Biological Process RNA processingManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Nucleus
Cytoplasm
Cell projection, dendrite
Localizes in mRNA granules in dentrites.
PTM
Arg-105 is dimethylated, probably to asymmetric dimethylarginine.
Phosphorylated.
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Anti-RBM3 antibodies

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Mouse Anti-RBM3 Recombinant Antibody (CL0296) (CBMAB-R1733-CN)

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Target: RBM3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CL0296
Application*: WB, IH, IF, P
Datasheet SDS

Mouse Anti-RBM3 Recombinant Antibody (CBCNR-301) (CBMAB-R1731-CN)

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Target: RBM3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBCNR-301
Application*: WB, P
Datasheet SDS

Mouse Anti-RBM3 Recombinant Antibody (CBCNR-300) (CBMAB-R1730-CN)

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Target: RBM3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBCNR-300
Application*: E, WB, P
Datasheet SDS

Mouse Anti-RBM3 Recombinant Antibody (4D6) (CBMAB-R1729-CN)

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Target: RBM3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4D6
Application*: E, IH, WB
Datasheet SDS

Rabbit Anti-RBM3 Recombinant Antibody (CBCNR-299) (CBMAB-R0157-CN)

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Target: RBM3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBCNR-299
Application*: WB, IF
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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