RBM3

This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have been characterized although some of these variants fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq]

RNA binding motif (RNP1, RRM) protein 3

Cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. Reduces the relative abundance of microRNAs, when overexpressed. Enhances phosphorylation of translation initiation factors and active polysome formation (By similarity).

Biological Process positive regulation of mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of translationISS:UniProtKB
Biological Process regulation of translationISS:UniProtKB
Biological Process RNA processingManual Assertion Based On ExperimentTAS:ProtInc

Nucleus
Cytoplasm
Cell projection, dendrite
Localizes in mRNA granules in dentrites.

Arg-105 is dimethylated, probably to asymmetric dimethylarginine.
Phosphorylated.