SNTB2

Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. [provided by RefSeq]

syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)

Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN.

Membrane
Cytoplasmic vesicle, secretory vesicle membrane
Cell junction
Cytoplasm, cytoskeleton
Membrane-associated. In muscle, it is exclusively localized at the neuromuscular junction (By similarity).
In insulinoma cell line, it is enriched in secretory granules

Phosphorylated. Partially dephosphorylated upon insulin stimulation.