SNTB2

Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. [provided by RefSeq]
Full Name
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
Function
Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN.
Cellular Location
Membrane
Cytoplasmic vesicle, secretory vesicle membrane
Cell junction
Cytoplasm, cytoskeleton
Membrane-associated. In muscle, it is exclusively localized at the neuromuscular junction (By similarity).
In insulinoma cell line, it is enriched in secretory granules
PTM
Phosphorylated. Partially dephosphorylated upon insulin stimulation.
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Anti-SNTB2 antibodies

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Mouse Anti-SNTB2 Recombinant Antibody (3F12) (CBMAB-A8428-LY)

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Target: SNTB2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3F12
Application*: SE, E
Datasheet SDS

Mouse Anti-SNTB2 Recombinant Antibody (CBXS-3703) (CBMAB-S0978-CQ)

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Target: SNTB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Amphibian, Dog, Chicken, Human, Mouse, Rat
Clone: CBXS-3703
Application*: F, IC, IF, IP, WB
Datasheet SDS

Mouse Anti-SNTB2 Recombinant Antibody (CBXS-5608) (CBMAB-S0486-CQ)

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Target: SNTB2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-5608
Application*: E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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