Mouse Anti-SNTB2 Recombinant Antibody (CBXS-5608) (CBMAB-S0486-CQ)

Name: Mouse Anti-SNTB2 Recombinant Antibody (CBXS-5608)
SKU: CBMAB-S0486-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-5608

Application

ELISA

Immunogen

Partial recombinant corresponding to aa116-211 from human SNTB2 (NP_006741) with GST tag

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)

Introduction

Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.

Entrez Gene ID

6645

UniProt ID

Q13425

Alternative Names

Syntrophin Beta 2; Syntrophin, Beta 2 (Dystrophin-Associated Protein A1, 59kDa, Basic Component 2); 59 KDa Dystrophin-Associated Protein A1 Basic Component 2; Syntrophin-3; D16S2531E; SNT2B2; SNTL;

Function

Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN.

Cellular Location

Membrane
Cytoplasmic vesicle, secretory vesicle membrane
Cell junction
Cytoplasm, cytoskeleton
Membrane-associated. In muscle, it is exclusively localized at the neuromuscular junction (By similarity).
In insulinoma cell line, it is enriched in secretory granules

PTM

Phosphorylated. Partially dephosphorylated upon insulin stimulation.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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