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Mouse Anti-SNTB2 Recombinant Antibody (CBXS-3703) (CBMAB-S0978-CQ)

This product is a mouse antibody that recognizes SNTB2. The antibody CBXS-3703 can be used for immunoassay techniques such as: FC, ICC, IF, IP, WB.
See all SNTB2 antibodies

Summary

Host Animal
Mouse
Specificity
Amphibian, Dog, Chicken, Human, Mouse, Rat
Clone
CBXS-3703
Antibody Isotype
IgG1
Application
FC, ICC, IF, IP, WB

Basic Information

Immunogen
Whole purified syntrophin from Torpedo californica electric organ postsynaptic membrane
Specificity
Amphibian, Dog, Chicken, Human, Mouse, Rat
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 1 mg/mL BSA
Preservative
0.05% sodium azide
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
Introduction
Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.
Entrez Gene ID
Human6645
Mouse20650
Rat689421
Chicken769654
Dog479675
UniProt ID
HumanQ13425
MouseQ61235
RatD3ZMX6
ChickenR4GLT4
DogA0A8I3N2P8
Alternative Names
Syntrophin Beta 2; Syntrophin, Beta 2 (Dystrophin-Associated Protein A1, 59kDa, Basic Component 2); 59 KDa Dystrophin-Associated Protein A1 Basic Component 2; Syntrophin-3; D16S2531E; SNT2B2; SNTL;
Function
Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN.
Cellular Location
Membrane
Cytoplasmic vesicle, secretory vesicle membrane
Cell junction
Cytoplasm, cytoskeleton
Membrane-associated. In muscle, it is exclusively localized at the neuromuscular junction (By similarity).
In insulinoma cell line, it is enriched in secretory granules
PTM
Phosphorylated. Partially dephosphorylated upon insulin stimulation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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