SORCS3
This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein. [provided by RefSeq]
Full Name
sortilin-related VPS10 domain containing receptor 3
Biological Process
Biological Process learningIEA:Ensembl
Biological Process memoryIEA:Ensembl
Biological Process neuropeptide signaling pathway1 PublicationNAS:UniProtKB
Biological Process regulation of long-term synaptic depressionIEA:Ensembl
Biological Process memoryIEA:Ensembl
Biological Process neuropeptide signaling pathway1 PublicationNAS:UniProtKB
Biological Process regulation of long-term synaptic depressionIEA:Ensembl
Cellular Location
Membrane
Topology
Lumenal: 34-1125
Helical: 1126-1146
Cytoplasmic: 1147-1222
Helical: 1126-1146
Cytoplasmic: 1147-1222
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Anti-SORCS3 antibodies
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Target: SORCS3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-3504
Application*: E, WB
Target: SORCS3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-3017
Application*: E, WB
Target: SORCS3
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: CBXS-1785
Application*: WB
Target: SORCS3
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBXS-1784
Application*: WB, IH
Target: SORCS3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-0650
Application*: E, WB
More Infomation
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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