STIP1
STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM
Full Name
STIP1
Function
Acts as a co-chaperone for HSP90AA1 (PubMed:27353360).
Mediates the association of the molecular chaperones HSPA8/HSC70 and HSP90 (By similarity).
Mediates the association of the molecular chaperones HSPA8/HSC70 and HSP90 (By similarity).
Biological Process
Biological Process cellular response to interleukin-7IEA:Ensembl
Biological Process protein foldingIEA:InterPro
Biological Process protein foldingIEA:InterPro
Cellular Location
Cytoplasm
Nucleus
Dynein axonemal particle
Nucleus
Dynein axonemal particle
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Anti-STIP1 antibodies
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CompareTarget: STIP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: 2E11
Application*: WB, E
Target: STIP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBNH-095
Application*: E, WB
Target: STIP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Chicken
Clone: DS14F5
Application*: IP, WB
Target: STIP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBXS-1553
Application*: WB, IP, P
Target: STIP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBXS-1552
Application*: WB, IP, P, IF
Target: STIP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-0778
Application*: E, IC, IH, WB
Target: STIP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Chicken
Clone: CBXS-0777
Application*: IP, WB
Target: STIP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-4991
Application*: E, IF, IP, WB
Target: STIP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-4521
Application*: E, WB, P, F
Target: STIP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-4514
Application*: E, WB, P, F
Target: STIP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBXS-4051
Application*: E, WB, P, IF
Target: STIP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4B6
Application*: E, IF, P, IP, WB
Target: STIP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1C6
Application*: E, IF, WB
Target: STIP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1B10
Application*: E, WB
Target: STIP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1E3
Application*: E, IF, P, WB
Target: STIP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2E1
Application*: E, F, IF, P, WB
Target: STIP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey, Hamster, Cattle
Clone: CBFYH-3663
Application*: WB
Target: STIP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey, Cattle
Clone: CBFYH-3662
Application*: WB, IF, F
Target: STIP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Frog, Sheep, Rabbit, Pig, Monkey, Mink, Hamster, Guinea pig, Dog, Chicken, Cattle
Clone: CBFYH-3661
Application*: IH, IP, WB
Target: STIP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 3E4
Application*: E, WB
Target: STIP1
Specificity: Human
Target: STIP1
Specificity: Human
Target: STIP1
Specificity: Human
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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