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Rabbit Anti-STIP1 Recombinant Antibody (CBXS-1553) (CBMAB-S4402-CQ)

This product is a rabbit antibody that recognizes STIP1. The antibody CBXS-1553 can be used for immunoassay techniques such as: WB, IP, IHC-P.
See all STIP1 antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse, Rat, Human
Clone
CBXS-1553
Antibody Isotype
IgG
Application
WB, IP, IHC-P

Basic Information

Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
STIP1
Introduction
STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones.
Entrez Gene ID
Human10963
Mouse20867
Rat192277
UniProt ID
HumanP31948
MouseQ60864
RatO35814
Alternative Names
HOP; P60; STI1; STI1L; HEL-S-94n; IEF-SSP-3521
Function
Acts as a co-chaperone for HSP90AA1 (PubMed:27353360).
Mediates the association of the molecular chaperones HSPA8/HSC70 and HSP90 (By similarity).
Biological Process
Biological Process cellular response to interleukin-7IEA:Ensembl
Biological Process protein foldingIEA:InterPro
Cellular Location
Cytoplasm
Nucleus
Dynein axonemal particle
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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