TFCP2

This gene encodes a transcription factor that binds the alpha-globin promoter and activates transcription of the alpha-globin gene. The encoded protein regulates erythroid gene expression, plays a role in the transcriptional switch of globin gene promoters, and it activates many other cellular and viral gene promoters. The gene product interacts with certain inflammatory response factors, and polymorphisms of this gene may be involved in the pathogenesis of Alzheimer's disease. [provided by RefSeq, Mar 2010]
Full Name
TFCP2 Gene(Protein Coding) Transcription Factor CP2
Function
Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1 (By similarity).
Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter.
Biological Process
Biological Process mRNA transcription by RNA polymerase IISource:UniProtKB1 Publication
Biological Process positive regulation of transcription by RNA polymerase IISource:UniProtKB1 Publication
Biological Process regulation of transcription by RNA polymerase IISource:UniProtKB1 Publication
Cellular Location
Nucleus
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Anti-TFCP2 antibodies

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TFCP2 Matched Antibody Pair (1198) (APMAB-1198LY)

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Target: TFCP2
Specificity: Human
Datasheet SDS

Rabbit Anti-TFCP2 Recombinant Antibody (D1S3V) (CBMAB-CP2739-LY)

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Target: TFCP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat, Monkey, Mouse, Frog, Zebrafish, Cattle
Clone: D1S3V
Application*: WB, IP
Datasheet SDS

Rabbit Anti-TFCP2 Recombinant Antibody (CBYJT-2649) (CBMAB-T1828-YJ)

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Target: TFCP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat, Monkey, Mouse, Frog, Zebrafish, Cattle
Clone: CBYJT-2649
Application*: WB, IP
Datasheet SDS

Mouse Anti-TFCP2 Recombinant Antibody (CBYJT-2648) (CBMAB-T1827-YJ)

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Target: TFCP2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJT-2648
Application*: E, WB
Datasheet SDS

Mouse Anti-TFCP2 Recombinant Antibody (CBYJT-2647) (CBMAB-T1826-YJ)

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Target: TFCP2
Host: Mouse
Antibody Isotype: IgG2a, λ
Specificity: Human
Clone: CBYJT-2647
Application*: E, WB
Datasheet SDS

Mouse Anti-TFCP2 Recombinant Antibody (37) (CBMAB-C5581-LY)

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Target: TFCP2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 37
Application*: WB
Datasheet SDS

Mouse Anti-TFCP2 Recombinant Antibody (3) (CBMAB-C5431-LY)

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Target: TFCP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3
Application*: WB
Datasheet SDS

Mouse Anti-TFCP2 Recombinant Antibody (CBYJL-2056) (CBMAB-L2184-YJ)

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Target: TFCP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Mouse, Rat
Clone: CBYJL-2056
Application*: WB, IF
Datasheet SDS

Mouse Anti-TFCP2 Monoclonal Antibody (3B1) (CBMAB-0248-LY)

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Target: TFCP2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 3B1
Application*: IP, M, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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