Mouse Anti-TFCP2 Recombinant Antibody (3) (CBMAB-C5431-LY)

Name: Mouse Anti-TFCP2 Recombinant Antibody (3)
SKU: CBMAB-C5431-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

Application

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Concentration

1 mg/ml

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

TFCP2 Gene(Protein Coding) Transcription Factor CP2

Introduction

This gene encodes a transcription factor that binds the alpha-globin promoter and activates transcription of the alpha-globin gene. The encoded protein regulates erythroid gene expression, plays a role in the transcriptional switch of globin gene promoters, and it activates many other cellular and viral gene promoters. The gene product interacts with certain inflammatory response factors, and polymorphisms of this gene may be involved in the pathogenesis of Alzheimer's disease. [provided by RefSeq, Mar 2010]

Entrez Gene ID

7024

UniProt ID

Q12800

Alternative Names

Transcription Factor CP2; SAA3 Enhancer Factor; SEF; LSF; Alpha-Globin Transcription Factor CP2; Transcription Factor LSF; TFCP2C; LBP1C; LSF1D;

Function

Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1 (By similarity).
Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter.

Biological Process

Biological Process mRNA transcription by RNA polymerase IISource:UniProtKB1 Publication
Biological Process positive regulation of transcription by RNA polymerase IISource:UniProtKB1 Publication
Biological Process regulation of transcription by RNA polymerase IISource:UniProtKB1 Publication

Cellular Location

Nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

TFCP2 Matched Antibody Pair (1198) (CAT#: APMAB-1198LY)

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Mouse Anti-TFCP2 Monoclonal Antibody (3B1) (CAT#: CBMAB-0248-LY)

Rabbit Anti-TFCP2 Recombinant Antibody (CBYJT-2649) (CAT#: CBMAB-T1828-YJ)

TFCP2 Matched Antibody Pair (1198) (CAT#: APMAB-1198LY)

Mouse Anti-TFCP2 Recombinant Antibody (37) (CAT#: CBMAB-C5581-LY)

Mouse Anti-TFCP2 Recombinant Antibody (CBYJT-2647) (CAT#: CBMAB-T1826-YJ)

Mouse Anti-TFCP2 Recombinant Antibody (CBYJL-2056) (CAT#: CBMAB-L2184-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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