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Mouse Anti-TFCP2 Recombinant Antibody (CBYJT-2648) (CBMAB-T1827-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TFCP2 (Transcription Factor CP2). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all TFCP2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-2648
Antibody Isotype
IgG2a
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TFCP2 Gene(Protein Coding) Transcription Factor CP2
Introduction
TFCP2 is a transcription factor that binds the alpha-globin promoter and activates transcription of the alpha-globin gene. TFCP2 regulates erythroid gene expression, plays a role in the transcriptional switch of globin gene promoters, and it activates many other cellular and viral gene promoters. TFCP2 interacts with certain inflammatory response factors, and polymorphisms of TFCP2 may be involved in the pathogenesis of Alzheimer's disease.
Entrez Gene ID
7024
UniProt ID
Q12800
Alternative Names
Transcription Factor CP2; SAA3 Enhancer Factor; SEF; LSF; Alpha-Globin Transcription Factor CP2; Transcription Factor LSF; TFCP2C; LBP1C; LSF1D
Function
Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1 (By similarity).
Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter.
Biological Process
Biological Process mRNA transcription by RNA polymerase IISource:UniProtKB1 Publication
Biological Process positive regulation of transcription by RNA polymerase IISource:UniProtKB1 Publication
Biological Process regulation of transcription by RNA polymerase IISource:UniProtKB1 Publication
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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