TFF1

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]
Full Name
TFF1 Gene(Protein Coding) Trefoil Factor 1
Function
Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine.
Biological Process
Biological Process carbohydrate metabolic processSource:ProtInc1 Publication
Biological Process cell differentiationSource:Ensembl
Biological Process cell population proliferationSource:Ensembl
Biological Process maintenance of gastrointestinal epitheliumSource:GO_Central1 Publication
Biological Process negative regulation of cell population proliferationSource:Ensembl
Biological Process response to immobilization stressSource:Ensembl
Biological Process response to iron ionSource:Ensembl
Biological Process response to peptide hormoneSource:Ensembl
Cellular Location
Secreted
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Anti-TFF1 antibodies

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Rabbit Anti-TFF1 Recombinant Antibody (D2Y1J) (CBMAB-CP2743-LY)

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Target: TFF1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: D2Y1J
Application*: WB, P
Datasheet SDS

Mouse Anti-TFF1 Recombinant Antibody (M2) (CBMAB-A9047-LY)

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Target: TFF1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: M2
Application*: WB, E
Datasheet SDS

Mouse Anti-TFF1 Recombinant Antibody (M1) (CBMAB-A9046-LY)

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Target: TFF1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: M1
Application*: WB, E
Datasheet SDS

Mouse Anti-TFF1 Recombinant Antibody (3H5) (CBMAB-A9045-LY)

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Target: TFF1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3H5
Application*: WB, E
Datasheet SDS

Recombinant Mouse Anti-TFF1 Recombinant Antibody (PS2GE2) (CBMAB-XB1123-YC)

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Target: TFF1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: PS2GE2
Application*: F, IH, IF, IP, WB
Datasheet SDS

Recombinant Mouse Anti-TFF1 Recombinant Antibody (PS2GE1) (CBMAB-XB1122-YC)

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Target: TFF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: PS2GE1
Application*: IH, IP
Datasheet SDS

Mouse Anti-TFF1 Recombinant Antibody (SPM573) (CBMAB-T1864-YJ)

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Target: TFF1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: SPM573
Application*: WB, F, E, IC, IF, IP, P, C, MC
Datasheet SDS

Mouse Anti-TFF1 Recombinant Antibody (GE2) (CBMAB-T1863-YJ)

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Target: TFF1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: GE2
Application*: WB, F, E, IC, IF, IP, P, C, MC
Datasheet SDS

Mouse Anti-TFF1 Recombinant Antibody (SPM313) (CBMAB-T1861-YJ)

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Target: TFF1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Monkey
Clone: SPM313
Application*: F, P, IF, MC
Datasheet SDS

Rabbit Anti-TFF1 Recombinant Antibody (CBYJT-2677) (CBMAB-T1860-YJ)

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Target: TFF1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-2677
Application*: WB, P
Datasheet SDS

Mouse Anti-TFF1 Recombinant Antibody (CBYJT-2676) (CBMAB-T1859-YJ)

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Target: TFF1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-2676
Application*: WB, F, IH, IC, IF, IP, P, MC
Datasheet SDS

Mouse Anti-TFF1 Recombinant Antibody (CBYJT-2675) (CBMAB-T1858-YJ)

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Target: TFF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-2675
Application*: IP, P
Datasheet SDS

Mouse Anti-TFF1 Recombinant Antibody (pS2.1) (CBMAB-T1857-YJ)

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Target: TFF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: pS2.1
Application*: P
Datasheet SDS

Rabbit Anti-TFF1 Recombinant Antibody (CBYJT-2674) (CBMAB-T1856-YJ)

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Target: TFF1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-2674
Application*: WB, IP, P, IC
Datasheet SDS

Mouse Anti-TFF1 Recombinant Antibody (CF432) (CBMAB-FT079LY)

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Target: TFF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CF432
Application*: ELISA, WB
Datasheet SDS

Rabbit Anti-TFF1 Recombinant Antibody (CBWJC-3482) (CBMAB-C4712WJ)

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Target: TFF1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBWJC-3482
Application*: WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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