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TFF1

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]
Full Name
TFF1 Gene(Protein Coding) Trefoil Factor 1
Function
Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine.
Biological Process
Biological Process carbohydrate metabolic processSource:ProtInc1 Publication
Biological Process cell differentiationSource:Ensembl
Biological Process cell population proliferationSource:Ensembl
Biological Process maintenance of gastrointestinal epitheliumSource:GO_Central1 Publication
Biological Process negative regulation of cell population proliferationSource:Ensembl
Biological Process response to immobilization stressSource:Ensembl
Biological Process response to iron ionSource:Ensembl
Biological Process response to peptide hormoneSource:Ensembl
Cellular Location
Secreted

Anti-TFF1 antibodies

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Target: TFF1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-2674
Application*: WB, IP, P, IC
Target: TFF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: pS2.1
Application*: P
Target: TFF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-2675
Application*: IP, P
Target: TFF1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-2676
Application*: WB, F, IH, IC, IF, IP, P, MC
Target: TFF1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-2677
Application*: WB, P
Target: TFF1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Monkey
Clone: SPM313
Application*: F, P, IF, MC
Target: TFF1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: GE2
Application*: WB, F, E, IC, IF, IP, P, C, MC
Target: TFF1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: SPM573
Application*: WB, F, E, IC, IF, IP, P, C, MC
Target: TFF1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBWJC-3482
Application*: WB
Target: TFF1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3H5
Application*: WB, E
Target: TFF1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: M1
Application*: WB, E
Target: TFF1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: M2
Application*: WB, E
Target: TFF1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: D2Y1J
Application*: WB, P
Target: TFF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CF432
Application*: ELISA, WB
Target: TFF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: PS2GE1
Application*: IH, IP
Target: TFF1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: PS2GE2
Application*: F, IH, IF, IP, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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