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TFF1

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]

Full Name

TFF1 Gene(Protein Coding) Trefoil Factor 1

Function

Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine.

Biological Process

Biological Process carbohydrate metabolic processSource:ProtInc1 Publication
Biological Process cell differentiationSource:Ensembl
Biological Process cell population proliferationSource:Ensembl
Biological Process maintenance of gastrointestinal epitheliumSource:GO_Central1 Publication
Biological Process negative regulation of cell population proliferationSource:Ensembl
Biological Process response to immobilization stressSource:Ensembl
Biological Process response to iron ionSource:Ensembl
Biological Process response to peptide hormoneSource:Ensembl

Cellular Location

Secreted

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Anti-TFF1 antibodies

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Rabbit Anti-TFF1 Recombinant Antibody (D2Y1J) (CBMAB-CP2743-LY)

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Target: TFF1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: D2Y1J

Application*: WB, P

Mouse Anti-TFF1 Recombinant Antibody (M2) (CBMAB-A9047-LY)

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Target: TFF1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: M2

Application*: WB, E

Mouse Anti-TFF1 Recombinant Antibody (M1) (CBMAB-A9046-LY)

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Target: TFF1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: M1

Application*: WB, E

Mouse Anti-TFF1 Recombinant Antibody (3H5) (CBMAB-A9045-LY)

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Target: TFF1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 3H5

Application*: WB, E

Recombinant Mouse Anti-TFF1 Recombinant Antibody (PS2GE2) (CBMAB-XB1123-YC)

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Target: TFF1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: PS2GE2

Application*: F, IH, IF, IP, WB

Recombinant Mouse Anti-TFF1 Recombinant Antibody (PS2GE1) (CBMAB-XB1122-YC)

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Target: TFF1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: PS2GE1

Application*: IH, IP

Mouse Anti-TFF1 Recombinant Antibody (SPM573) (CBMAB-T1864-YJ)

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Target: TFF1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: SPM573

Application*: WB, F, E, IC, IF, IP, P, C, MC

Mouse Anti-TFF1 Recombinant Antibody (GE2) (CBMAB-T1863-YJ)

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Target: TFF1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: GE2

Application*: WB, F, E, IC, IF, IP, P, C, MC

Mouse Anti-TFF1 Recombinant Antibody (SPM313) (CBMAB-T1861-YJ)

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Target: TFF1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Monkey

Clone: SPM313

Application*: F, P, IF, MC

Rabbit Anti-TFF1 Recombinant Antibody (CBYJT-2677) (CBMAB-T1860-YJ)

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Target: TFF1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJT-2677

Application*: WB, P

Mouse Anti-TFF1 Recombinant Antibody (CBYJT-2676) (CBMAB-T1859-YJ)

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Target: TFF1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYJT-2676

Application*: WB, F, IH, IC, IF, IP, P, MC

Mouse Anti-TFF1 Recombinant Antibody (CBYJT-2675) (CBMAB-T1858-YJ)

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Target: TFF1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-2675

Application*: IP, P

Mouse Anti-TFF1 Recombinant Antibody (pS2.1) (CBMAB-T1857-YJ)

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Target: TFF1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: pS2.1

Application*: P

Rabbit Anti-TFF1 Recombinant Antibody (CBYJT-2674) (CBMAB-T1856-YJ)

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Target: TFF1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJT-2674

Application*: WB, IP, P, IC

Human Recombinant TFF1 protein, His Tag (V2LY-0526-LY7161)

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Target: TFF1

Expressed Host: HEK293 Cells

Sequence: Amino Acid: 1-84

Tag: His Tag

Mouse Anti-TFF1 Recombinant Antibody (CF432) (CBMAB-FT079LY)

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Target: TFF1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse

Clone: CF432

Application*: ELISA, WB

Rabbit Anti-TFF1 Recombinant Antibody (CBWJC-3482) (CBMAB-C4712WJ)

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Target: TFF1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse

Clone: CBWJC-3482

Application*: WB

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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