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Mouse Anti-TFF1 Recombinant Antibody (SPM313) (CBMAB-T1861-YJ)


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Summary

Host Animal
Mouse
Specificity
Human, Monkey
Clone
SPM313
Antibody Isotype
IgG1, κ
Application
FC, IHC-P, IF, CyTOF

Basic Information

Immunogen
Synthetic peptide of 28 amino acid residues corresponding to CFDDTVRGVPWCFYPNTIDVPPEEECEF (aa57-84) from the C-terminus of human pS2
Specificity
Human, Monkey
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 57-84

Target

Full Name
TFF1 Gene(Protein Coding) Trefoil Factor 1
Introduction
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. TFF1, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors.
Entrez Gene ID
Human7031
Monkey100423966
UniProt ID
HumanP04155
MonkeyA0A5F8AHB4
Alternative Names
Trefoil Factor 1; Breast Cancer Estrogen-Inducible Protein; Polypeptide P1.A; Protein PS2; HP1.A; PNR-2; BCEI
Function
Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine.
Biological Process
Biological Process carbohydrate metabolic processSource:ProtInc1 Publication
Biological Process cell differentiationSource:Ensembl
Biological Process cell population proliferationSource:Ensembl
Biological Process maintenance of gastrointestinal epitheliumSource:GO_Central1 Publication
Biological Process negative regulation of cell population proliferationSource:Ensembl
Biological Process response to immobilization stressSource:Ensembl
Biological Process response to iron ionSource:Ensembl
Biological Process response to peptide hormoneSource:Ensembl
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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