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Mouse Anti-TFF1 Recombinant Antibody (M1) (CBMAB-A9046-LY)

The product is antibody recognizes TFF1. The antibody M1 immunoassay techniques such as: WB, ELISA.
See all TFF1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
M1
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
TFF1 (AAH32811.1, 1 a.a. ~ 84 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
TFF1 Gene(Protein Coding) Trefoil Factor 1
Introduction
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq]
Entrez Gene ID
7031
UniProt ID
P04155
Alternative Names
BCEI; D21S21; HP1.A; HPS2; pNR-2; pS2
Function
Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine.
Biological Process
Biological Process carbohydrate metabolic processSource:ProtInc1 Publication
Biological Process cell differentiationSource:Ensembl
Biological Process cell population proliferationSource:Ensembl
Biological Process maintenance of gastrointestinal epitheliumSource:GO_Central1 Publication
Biological Process negative regulation of cell population proliferationSource:Ensembl
Biological Process response to immobilization stressSource:Ensembl
Biological Process response to iron ionSource:Ensembl
Biological Process response to peptide hormoneSource:Ensembl
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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