TRMT2A
TRMT2A is of unknown function. However, it is orthologous to the mouse Trmt2a gene and contains an RNA methyltransferase domain. Expression of this gene varies during the cell cycle, with aberrant expression being a possible biomarker in certain breast cancers.
Full Name
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
Function
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine in tRNAs and some mRNAs (PubMed:31361898, PubMed:33799331, PubMed:34556860).
Mainly catalyzes the methylation of uridine at position 54 (m5U54) in cytosolic tRNAs (PubMed:31361898, PubMed:33799331).
Also able to mediate the formation of 5-methyl-uridine in some mRNAs (PubMed:34123281).
Mainly catalyzes the methylation of uridine at position 54 (m5U54) in cytosolic tRNAs (PubMed:31361898, PubMed:33799331).
Also able to mediate the formation of 5-methyl-uridine in some mRNAs (PubMed:34123281).
Biological Process
Biological Process mRNA processing Source:UniProtKB-KW
Cellular Location
Cytoplasm, cytosol
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Anti-TRMT2A antibodies
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CompareTarget: TRMT2A
Sensitivity: 0.0074 ng/mL
Detection Range: 0.015-3 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: TRMT2A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-4879
Application*: E, WB
Target: TRMT2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4878
Application*: IF, P, WB
Target: TRMT2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4877
Application*: WB
Target: TRMT2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4876
Application*: WB, IH, IF
Target: TRMT2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4875
Application*: WB
Target: TRMT2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4874
Application*: WB, IH, IF
Target: TRMT2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4873
Application*: WB, IH
Target: TRMT2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4872
Application*: WB, IH, IF
Target: TRMT2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4871
Application*: WB, IF, F
Target: TRMT2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4870
Application*: WB, IH
Target: TRMT2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4869
Application*: WB, IH, IF, F
Target: TRMT2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2811
Application*: WB, F, IH, IF
Target: TRMT2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2810
Application*: WB, P, IF
Target: TRMT2A
Host: Rat
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYH-3315
Application*: E, WB, P
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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