TRPC7

TRPC7 (TRPC7 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

Full Name

Transient Receptor Potential Cation Channel Subfamily C Member 7

Function

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity).
May also be activated by intracellular calcium store depletion.

Biological Process

Biological Process calcium ion transmembrane transport Source:GO_Central1 Publication
Biological Process manganese ion transport Source:GO_Central1 Publication
Biological Process regulation of cytosolic calcium ion concentration Source:GO_Central1 Publication
Biological Process single fertilization Source:GO_Central1 Publication

Cellular Location

Cell membrane
Nucleus envelope

Topology

Cytoplasmic: 1-351
Helical: 352-372
Extracellular: 373-383
Helical: 384-404
Cytoplasmic: 405-465
Helical: 466-486
Extracellular: 487-537
Helical: 538-558
Cytoplasmic: 559-581
Helical: 582-602
Extracellular: 603-651
Helical: 652-672
Cytoplasmic: 673-862

PTM

Phosphorylation by PRKG1 at Thr-15 negatively regulates TRPC7 activity.

Anti-TRPC7 antibodies

Mouse Anti-TRPC7 Recombinant Antibody (CBYJT-4911) (CBMAB-T4460-YJ)

Datasheet

SDS

Target: TRPC7

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Rat

Clone: CBYJT-4911

Application*: IF, IH, IP, WB

Mouse Anti-TRPC7 Recombinant Antibody (S64A-36) (CBMAB-T4461-YJ)

Datasheet

SDS

Target: TRPC7

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Rat

Clone: S64A-36

Application*: WB, IH, IC, IF, IP, AM

Mouse Anti-TRPC7 Recombinant Antibody (CBYJT-4912) (CBMAB-T4462-YJ)

Datasheet

SDS

Target: TRPC7

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Rat

Clone: CBYJT-4912

Application*: IC, P, IP, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)