TXN2

TXN2 is a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. TXN2 may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.

Thioredoxin 2

Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. Possesses a dithiol-reducing activity.

Biological Process cell redox homeostasis Source:GO_Central1 Publication
Biological Process cellular response to nutrient levels Source:Ensembl
Biological Process response to axon injury Source:Ensembl
Biological Process response to glucose Source:Ensembl
Biological Process response to hormone Source:Ensembl
Biological Process response to hypoxia Source:Ensembl
Biological Process response to organic cyclic compound Source:Ensembl
Biological Process response to oxidative stress Source:Ensembl
Biological Process response to xenobiotic stimulus Source:Ensembl

Mitochondrion

Combined oxidative phosphorylation deficiency 29 (COXPD29):
An autosomal recessive, infantile-onset, neurodegenerative disorder characterized by decreased activities of mitochondrial respiratory complexes I and III, severe cerebellar atrophy, epilepsy, dystonia, optic atrophy, and peripheral neuropathy.