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TXN2

TXN2 is a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. TXN2 may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.
Full Name
Thioredoxin 2
Function
Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. Possesses a dithiol-reducing activity.
Biological Process
Biological Process cell redox homeostasis Source:GO_Central1 Publication
Biological Process cellular response to nutrient levels Source:Ensembl
Biological Process response to axon injury Source:Ensembl
Biological Process response to glucose Source:Ensembl
Biological Process response to hormone Source:Ensembl
Biological Process response to hypoxia Source:Ensembl
Biological Process response to organic cyclic compound Source:Ensembl
Biological Process response to oxidative stress Source:Ensembl
Biological Process response to xenobiotic stimulus Source:Ensembl
Cellular Location
Mitochondrion
Involvement in disease
Combined oxidative phosphorylation deficiency 29 (COXPD29):
An autosomal recessive, infantile-onset, neurodegenerative disorder characterized by decreased activities of mitochondrial respiratory complexes I and III, severe cerebellar atrophy, epilepsy, dystonia, optic atrophy, and peripheral neuropathy.

Anti-TXN2 antibodies

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Target: TXN2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-5446
Application*: WB, E
Target: TXN2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-5447
Application*: P, IC, IF
Target: TXN2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-5448
Application*: E
Target: TXN2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-5449
Application*: E, WB
Target: TXN2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYJT-5450
Application*: WB, E, IC, IF
Target: TXN2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-5451
Application*: E
Target: TXN2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: CBYJT-5452
Application*: IP
Target: TXN2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBYJT-5453
Application*: WB, IP
Target: TXN2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBYJT-5454
Application*: WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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