Rabbit Anti-TXN2 Recombinant Antibody (CBYJT-5449) (CBMAB-T5057-YJ)

Name: Rabbit Anti-TXN2 Recombinant Antibody (CBYJT-5449)
SKU: CBMAB-T5057-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rabbit

Clone

CBYJT-5449

Application

ELISA, WB

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Thioredoxin 2

Introduction

TXN2 is a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. TXN2 may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.

Entrez Gene ID

25828

UniProt ID

Q99757

Alternative Names

Thioredoxin 2; MT-TRX; TRX2; MTRX; Thioredoxin, Mitochondrial; Mitochondrial Thioredoxin; Thioredoxin-2; COXPD29; TXN

Function

Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. Possesses a dithiol-reducing activity.

Biological Process

Biological Process cell redox homeostasis Source:GO_Central1 Publication
Biological Process cellular response to nutrient levels Source:Ensembl
Biological Process response to axon injury Source:Ensembl
Biological Process response to glucose Source:Ensembl
Biological Process response to hormone Source:Ensembl
Biological Process response to hypoxia Source:Ensembl
Biological Process response to organic cyclic compound Source:Ensembl
Biological Process response to oxidative stress Source:Ensembl
Biological Process response to xenobiotic stimulus Source:Ensembl

Cellular Location

Mitochondrion

Involvement in disease

Combined oxidative phosphorylation deficiency 29 (COXPD29):
An autosomal recessive, infantile-onset, neurodegenerative disorder characterized by decreased activities of mitochondrial respiratory complexes I and III, severe cerebellar atrophy, epilepsy, dystonia, optic atrophy, and peripheral neuropathy.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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