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Rabbit Anti-TXN2 Recombinant Antibody (CBYJT-5447) (CBMAB-T5055-YJ)

Provided herein is a Rabbit monoclonal antibody, which binds to TXN2 (Thioredoxin 2). The antibody can be used for immunoassay techniques, such as IHC-P, ICC, IF.
See all TXN2 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBYJT-5447
Antibody Isotype
IgG
Application
IHC-P, ICC, IF

Basic Information

Immunogen
Recombinant Human Thioredoxin-2 / TXN2 protein
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Thioredoxin 2
Introduction
TXN2 is a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. TXN2 may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.
Entrez Gene ID
UniProt ID
Alternative Names
Thioredoxin 2; MT-TRX; TRX2; MTRX; Thioredoxin, Mitochondrial; Mitochondrial Thioredoxin; Thioredoxin-2; COXPD29; TXN
Function
Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. Possesses a dithiol-reducing activity.
Biological Process
Biological Process cell redox homeostasis Source:GO_Central1 Publication
Biological Process cellular response to nutrient levels Source:Ensembl
Biological Process response to axon injury Source:Ensembl
Biological Process response to glucose Source:Ensembl
Biological Process response to hormone Source:Ensembl
Biological Process response to hypoxia Source:Ensembl
Biological Process response to organic cyclic compound Source:Ensembl
Biological Process response to oxidative stress Source:Ensembl
Biological Process response to xenobiotic stimulus Source:Ensembl
Cellular Location
Mitochondrion
Involvement in disease
Combined oxidative phosphorylation deficiency 29 (COXPD29):
An autosomal recessive, infantile-onset, neurodegenerative disorder characterized by decreased activities of mitochondrial respiratory complexes I and III, severe cerebellar atrophy, epilepsy, dystonia, optic atrophy, and peripheral neuropathy.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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