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USP16

This gene encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Anti-USP16 antibodies

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Cat Product Name Target Host Antibody Isotype Cross Reactivity Clone Application*
CBMAB-0293-LY Mouse Anti-USP16 Recombinant Antibody (1B2) USP16 Mouse IgG1 Human 1B2 IP, M, WB
CBMAB-U0020-CQ Mouse Anti-USP16 (aa 137-466) Recombinant Antibody (1B4) USP16 Mouse IgG2a Human 1B4 WB
PEP-062321CQ Human USP16 Peptide (QEGVMHKEY) USP16
PEP-192461CQ Mouse USP16 Peptide (SQTPVLREL) USP16
PEP-163019CQ Human USP16 Peptide (HPEDSEYEAEM) USP16
PEP-163018CQ Human USP16 Peptide (KRFQQAGFNLR) USP16
PEP-163017CQ Human USP16 Peptide (KRFQQAGFNL) USP16
PEP-163016CQ Human USP16 Peptide (AEENTRVLY) USP16
PEP-163015CQ Human USP16 Peptide (VAEENTRVL) USP16
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)