VSNL1
This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Full Name
Visinin-like protein 1
Function
Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.
Biological Process
Biological Process negative regulation of insulin secretion Source:Ensembl
Biological Process positive regulation of exocytosis Source:Ensembl
Biological Process positive regulation of insulin secretion involved in cellular response to glucose stimulus Source:Ensembl
Biological Process positive regulation of exocytosis Source:Ensembl
Biological Process positive regulation of insulin secretion involved in cellular response to glucose stimulus Source:Ensembl
Cellular Location
cytosol
membrane
membrane
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Anti-VSNL1 antibodies
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Target: VSNL1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Application*: IF, IHC, WB
Target: VSNL1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: D9L6L
Application*: WB, IP
Target: VSNL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Cattle
Clone: 3A9
Application*: IF, P, WB
Target: VSNL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Cattle
Clone: 2D11
Application*: WB, IC/IF
Target: VSNL1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Cattle, Chicken
Clone: 7G4
Application*: E
Target: VSNL1
Sensitivity: 0.027 ng/mL
Detection Range: 0.05-30 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: Vsnl1
Sensitivity: 0.0097 ng/mL
Detection Range: 0.02-4.5 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Target: VSNL1
Expressed Host: E. coli
Sequence: Amino Acid: 2-191
Target: VSNL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1C8
Application*: P
Target: VSNL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4G1
Application*: IH, WB
Target: VSNL1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2D5
Application*: IH, WB
Target: VSNL1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2F1-E3
Application*: WB
More Infomation
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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