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Mouse Anti-VSNL1 Recombinant Antibody (CBMAB-BR492LY)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application
IF: 1:1000 dilution, IHC: 1:300-1:500 dilution, WB: 0.1-0.5 μg/ml

Basic Information

Immunogen
Recombinant full length human protein
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
50% glycerol
Preservative
5mM sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Visinin-like protein 1
Introduction
This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Entrez Gene ID
Human7447
Mouse26950
Rat24877
UniProt ID
HumanP62760
MouseP62761
RatP62762
Alternative Names
Visinin-like protein 1;VILIP;VLP-1;Hippocalcin-like protein 3;HLP3;VSNL1;VISL1;
Function
Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.
Biological Process
Biological Process negative regulation of insulin secretion Source:Ensembl
Biological Process positive regulation of exocytosis Source:Ensembl
Biological Process positive regulation of insulin secretion involved in cellular response to glucose stimulus Source:Ensembl
Cellular Location
cytosol
membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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