Mouse Anti-VSNL1 Recombinant Antibody (1C8) (CBMAB-V0078-YC)

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Basic Information

Host Animal
Mouse
Clone
1C8
Application
IHC-P
Immunogen
Human recombinant protein fragment corresponding to amino acids 2-191 of human VSNL1 (NP_003376) produced in E. coli.
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Visinin-like protein 1
Introduction
VSNL1 is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. VSNL1 is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase.
Entrez Gene ID
UniProt ID
Alternative Names
Visinin Like 1; Hippocalcin-Like Protein 3; VILIP; VLP-1; HLP3; Visinin-Like Protein 1
Function
Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.
Biological Process
Biological Process negative regulation of insulin secretion Source:Ensembl
Biological Process positive regulation of exocytosis Source:Ensembl
Biological Process positive regulation of insulin secretion involved in cellular response to glucose stimulus Source:Ensembl
Cellular Location
cytosol
membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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