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Mouse Anti-BTN2A2 Recombinant Antibody (CBT3387) (V2LY-0625-LY902)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT3387
Antibody Isotype
IgG2a
Application
WB, ICC, FC

Basic Information

Immunogen
Purified recombinant fragment of human BTN2A2 (AA: extra 57-237) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
ICC1:200-1:1,000
FC1:200-1:400
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Butyrophilin Subfamily 2 Member A2
Entrez Gene ID
10385
UniProt ID
Q8WVV5
Function
Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
Biological Process
Adaptive immune response Source: Reactome
Negative regulation of activated T cell proliferation Source: UniProtKB
Negative regulation of cellular metabolic process Source: UniProtKB
Negative regulation of cytokine production Source: UniProtKB
Regulation of cytokine production Source: GO_Central
T cell receptor signaling pathway Source: GO_Central
Cellular Location
Membrane
Topology
Extracellular: 33-265 aa
Helical: 266-286 aa
Cytoplasmic: 287-523 aa
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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