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Mouse Anti-CALR3 Recombinant Antibody (CBXC-1965) (CBMAB-C5617-CQ)

This product is a mouse antibody that recognizes CALR3. The antibody CBXC-1965 can be used for immunoassay techniques such as: WB.
See all CALR3 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat, Dog, Monkey
Clone
CBXC-1965
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Full length human recombinant protein of human CALR3 (NP_659483)
Specificity
Human, Mouse, Rat, Dog, Monkey
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Calreticulin 3
Introduction
The protein encoded by this gene belongs to the calreticulin family, members of which are calcium-binding chaperones localized mainly in the endoplasmic reticulum. This protein is also localized to the endoplasmic reticulum lumen, however, its capacity for calcium-binding may be absent or much lower than other family members. This gene is specifically expressed in the testis, and may be required for sperm fertility. Mutation in this gene has been associated with familial hypertrophic cardiomyopathy.
Entrez Gene ID
Human125972
Mouse73316
Rat364529
Dog476680
Monkey716910
UniProt ID
HumanQ96L12
MouseQ9D9Q6
RatQ6AYG8
DogE2RGY6
MonkeyQ4R6K8
Alternative Names
Calreticulin 3; Calsperin; Cancer/Testis Antigen 93; Calreticulin-2; CRT2; Testis Secretory Sperm-Binding Protein Li 226n; Calreticulin-3; CMH19; CT93;
Function
During spermatogenesis, may act as a lectin-independent chaperone for specific client proteins such as ADAM3. Required for sperm fertility (By similarity).
CALR3 capacity for calcium-binding may be absent or much lower than that of CALR.
Biological Process
Cell differentiation Source: UniProtKB-KW
Endoplasmic reticulum unfolded protein response Source: GO_Central
Protein folding Source: GO_Central
Spermatogenesis Source: UniProtKB-KW
Cellular Location
Endoplasmic reticulum lumen
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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