CALR3

The protein encoded by this gene belongs to the calreticulin family, members of which are calcium-binding chaperones localized mainly in the endoplasmic reticulum. This protein is also localized to the endoplasmic reticulum lumen, however, its capacity for calcium-binding may be absent or much lower than other family members. This gene is specifically expressed in the testis, and may be required for sperm fertility. Mutation in this gene has been associated with familial hypertrophic cardiomyopathy. [provided by RefSeq, Dec 2011]
Full Name
Calreticulin 3
Function
During spermatogenesis, may act as a lectin-independent chaperone for specific client proteins such as ADAM3. Required for sperm fertility (By similarity).
CALR3 capacity for calcium-binding may be absent or much lower than that of CALR.
Biological Process
Cell differentiation Source: UniProtKB-KW
Endoplasmic reticulum unfolded protein response Source: GO_Central
Protein folding Source: GO_Central
Spermatogenesis Source: UniProtKB-KW
Cellular Location
Endoplasmic reticulum lumen
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Anti-CALR3 antibodies

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Mouse Anti-CALR3 Recombinant Antibody (CBXC-1097) (CBMAB-C1363-CQ)

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Target: CALR3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1097
Application*: WB
Datasheet SDS

Mouse Anti-CALR3 Recombinant Antibody (CBYY-C0901) (CBMAB-C2338-YY)

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Target: CALR3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYY-C0901
Application*: E, WB
Datasheet SDS

Mouse Anti-CALR3 Recombinant Antibody (CBFYC-0764) (CBMAB-C0819-FY)

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Target: CALR3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYC-0764
Application*: E, WB, IP
Datasheet SDS

Mouse Anti-CALR3 Recombinant Antibody (1D1) (CBMAB-C3792-LY)

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Target: CALR3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1D1
Application*: WB
Datasheet SDS

CALR3 Matched Antibody Pair (175) (APMAB-175LY)

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Target: CALR3
Specificity: Human
Datasheet SDS

CALR3 Matched Antibody Pair (174) (APMAB-174LY)

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Target: CALR3
Specificity: Human
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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