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Mouse Anti-CHD1L Recombinant Antibody (CBYY-C1961) (CBMAB-C3399-YY)

This product is mouse antibody that recognizes CHD1L . The antibody CBYY-C1961 can be used for immunoassay techniques such as: ICC, IP, WB
See all CHD1L antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C1961
Antibody Isotype
IgG1
Application
ICC, IP, WB

Basic Information

Immunogen
Partial sequence of recombinant full-length protein to human CHD1L
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Protein G purified
Buffer
0.05 mg/mL
Preservative
PBS, pH 7.4, 1% BSA, 40% glycerol
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Chromodomain Helicase DNA Binding Protein 1 Like
Entrez Gene ID
9557
UniProt ID
Q86WJ1
Alternative Names
Thy-1 Cell Surface Antigen; Thy-1 Antigen; CDw90; Thy-1 Membrane Glycoprotein; Thy-1 T-Cell Antigen; CD90 Antigen; CD90;
Function
DNA helicase which plays a role in chromatin-remodeling following DNA damage (PubMed:19661379, PubMed:29220653).
Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair (PubMed:19661379).
Able to catalyze nucleosome sliding in an ATP-dependent manner (PubMed:19661379).
Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding (PubMed:19661379, PubMed:29220653).
Biological Process
Cellular response to DNA damage stimulus Source: UniProtKB
Chromatin remodeling Source: UniProtKB
DNA repair Source: UniProtKB
Global genome nucleotide-excision repair Source: Reactome
Nucleotide-excision repair, DNA duplex unwinding Source: Reactome
Nucleotide-excision repair, DNA incision Source: Reactome
Nucleotide-excision repair, DNA incision, 3'-to lesion Source: Reactome
Nucleotide-excision repair, DNA incision, 5'-to lesion Source: Reactome
Nucleotide-excision repair, preincision complex assembly Source: Reactome
Nucleotide-excision repair, preincision complex stabilization Source: Reactome
Cellular Location
Nucleus. Localizes at sites of DNA damage. Probably recruited to DNA damage sites by PARylated PARP1.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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