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Mouse Anti-CLEC2D Recombinant Antibody (CBFYC-1920) (CBMAB-C1985-FY)

This product is mouse antibody that recognizes CLEC2D. The antibody CBFYC-1920 can be used for immunoassay techniques such as: WB.
See all CLEC2D antibodies

Summary

Host Animal
Mouse
Specificity
Mouse
Clone
CBFYC-1920
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Mouse OCIL
Specificity
Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.2% gelatin
Preservative
0.05% Sodium azide
Concentration
0.5 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
C-Type Lectin Domain Family 2 Member D
Introduction
This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified for this gene.
Entrez Gene ID
93694
UniProt ID
Q91V08
Alternative Names
Clrb; Ocil; Clr-b
Function
Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis (PubMed:20843815, PubMed:16339513).

Inhibits osteoclast formation (PubMed:14753741, PubMed:15123656).

Inhibits bone resorption (PubMed:14753741).

Modulates the release of interferon-gamma (PubMed:15104121).

Binds high molecular weight sulfated glycosaminoglycans (PubMed:15123656).
Biological Process
Cell surface receptor signaling pathway Source: ProtInc
Regulation of immune response Source: Reactome
Cellular Location
Cell membrane
Isoform 2&4: Endoplasmic reticulum
Topology
Cytoplasmic: 1-38
Helical: 39-59
Extracellular: 60-191
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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