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Mouse Anti-CLEC2D Recombinant Antibody (4C7) (CBMAB-C6743-LY)

This product is antibody recognizes CLEC2D. The antibody 4C7 immunoassay techniques such as: ELISA, IHC-P, WB.
See all CLEC2D antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4C7
Antibody Isotype
IgG1, κ
Application
ELISA, IHC-P, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
C-Type Lectin Domain Family 2 Member D
Introduction
This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Oct 2010]
Entrez Gene ID
29121
UniProt ID
Q9UHP7
Alternative Names
C-Type Lectin Domain Family 2 Member D; Lectin-Like Transcript 1; C-Type Lectin Superfamily 2, Member D; Lectin-Like NK Cell Receptor; Osteoclast Inhibitory Lectin; C-Type Lectin Related F;
Function
Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis (PubMed:20843815, PubMed:16339513).

Inhibits osteoclast formation (PubMed:14753741, PubMed:15123656).

Inhibits bone resorption (PubMed:14753741).

Modulates the release of interferon-gamma (PubMed:15104121).

Binds high molecular weight sulfated glycosaminoglycans (PubMed:15123656).
Biological Process
Cell surface receptor signaling pathway Source: ProtInc
Regulation of immune response Source: Reactome
Cellular Location
Cell membrane
Isoform 2&4: Endoplasmic reticulum
Topology
Cytoplasmic: 1-38
Helical: 39-59
Extracellular: 60-191
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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