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Mouse Anti-CRTAC1 Recombinant Antibody (C8510) (V2LY-1206-LY1235)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
C8510
Antibody Isotype
IgG2b
Application
IF

Basic Information

Immunogen
Recombinant human CRTAC1 Ser28-Cys661.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
IF(ICC)8-25 µg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS, Trehalose
Preservative
None
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Entrez Gene ID
55118
UniProt ID
Q9NQ79
Cellular Location
Extracellular matrix
PTM
O-glycosylated.
More Infomation

Yang, J., Fan, L., Liao, X., Cui, G., & Hu, H. (2021). CRTAC1 (Cartilage acidic protein 1) inhibits cell proliferation, migration, invasion and epithelial-mesenchymal transition (EMT) process in bladder cancer by downregulating Yin Yang 1 (YY1) to inactivate the TGF-β pathway. Bioengineered, 12(2), 9377-9389.

Félix, R. C., Anjos, L., Costa, R. A., Letsiou, S., & Power, D. M. (2021). Cartilage Acidic Protein a Novel Therapeutic Factor to Improve Skin Damage Repair?. Marine Drugs, 19(10), 541.

Styrkarsdottir, U., Lund, S. H., Saevarsdottir, S., Magnusson, M. I., Gunnarsdottir, K., Norddahl, G. L., ... & Stefansson, K. (2021). The CRTAC1 Protein in Plasma Is Associated With Osteoarthritis and Predicts Progression to Joint Replacement: A Large‐Scale Proteomics Scan in Iceland. Arthritis & Rheumatology, 73(11), 2025-2034.

Kuwashiro, T., Tanabe, K., Hayashi, C., Mizoguchi, T., Mori, K., Jinnouchi, J., ... & Okada, Y. (2021). Oxidized Albumin and Cartilage Acidic Protein-1 as Blood Biomarkers to Predict Ischemic Stroke Outcomes. Frontiers in neurology, 2233.

Letsiou, S., Manchado, M., Zografaki, M., Marka, S., Anjos, L., Skliros, D., ... & Power, D. M. (2021). Deciphering the role of cartilage protein 1 in human dermal fibroblasts: a transcriptomic approach. Functional & Integrative Genomics, 21(3), 503-511.

Sun, Y., Rong, X., Li, D., Lu, Y., & Ji, Y. (2020). NF-κB/cartilage acidic protein 1 promotes ultraviolet B irradiation-induced apoptosis of human lens epithelial cells. DNA and Cell Biology, 39(4), 513-521.

Letsiou, S., Félix, R. C., Cardoso, J. C., Anjos, L., Mestre, A. L., Gomes, H. L., & Power, D. M. (2020). Cartilage acidic protein 1 promotes increased cell viability, cell proliferation and energy metabolism in primary human dermal fibroblasts. Biochimie, 171, 72-78.

Anjos, L., Morgado, I., Guerreiro, M., Cardoso, J. C., Melo, E. P., & Power, D. M. (2017). Cartilage acidic protein 1, a new member of the beta‐propeller protein family with amyloid propensity. Proteins: Structure, Function, and Bioinformatics, 85(2), 242-255.

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For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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