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Rabbit Anti-EP300 (Phospho-Ser89) Recombinant Antibody (EG1110) (CBMAB-EN1307-LY)


See all EP300 (Phospho-Ser89) antibodies
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Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EG1110
Antibody Isotype
IgG
Application
IHC: 1:50~1:100 ELISA: 1:1000

Basic Information

Immunogen
The antibody was produced against synthesized phosphopeptide derived from human p300 around the phosphorylation site of serine 89 (S-G-SP-S-P).
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
E1A Binding Protein P300
Introduction
This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
Entrez Gene ID
Human2033
Mouse328572
Rat170915
UniProt ID
HumanQ09472
MouseB2RWS6
RatA0A0G2QC09
Alternative Names
E1A Binding Protein P300; EC 2.3.1.-; Protein Propionyltransferase P300; Histone Crotonyltransferase P300; Histone Butyryltransferase P300; Histone Acetyltransferase P300; E1A-Associated Protein P300; EC 2.3.1.48;
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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