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Rabbit Anti-F7 Recombinant Antibody (279) (CBMAB-C4516-LY)

This product is antibody recognizes F7. The antibody 279 immunoassay techniques such as: ELISA.
Host Animal
Rabbit
Application
ELISA
Immunogen
Recombinant Mouse Coagulation Factor VII protein
Antibody Isotype
IgG
Specificity
Mouse
Cross Reactivity
Mouse
Clone
279
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides. [provided by RefSeq, Aug 2015]
Cat CBMAB-C4516-LY
Conjugates
Size
Price $
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