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Mouse Anti-FBXL22 (AA 1-110) Recombinant Antibody (CBXF-0385) (CBMAB-F2229-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXF-0385
Antibody Isotype
IgG2a, κ
Application
ELISA, IF

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-110

Target

Full Name
F-Box And Leucine Rich Repeat Protein 22
Introduction
This gene encodes a member of the F-box protein family. This F-box protein interacts with S-phase kinase-associated protein 1A and cullin in order to form SCF complexes which function as ubiquitin ligases.
Entrez Gene ID
283807
UniProt ID
Q6P050
Alternative Names
F-Box And Leucine Rich Repeat Protein 22; F-Box And Leucine-Rich Protein 22; F-Box/LRR-Repeat Protein 22; Fbl22;
Research Area
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes ubiquitination of sarcomeric proteins alpha-actinin-2 (ACTN2) and filamin-C (FLNC).
Biological Process
Entrainment of circadian clock by photoperiod Source: GO_Central
G2/M transition of mitotic cell cycle Source: GO_Central
Proteasome-mediated ubiquitin-dependent protein catabolic process Source: MGI
Regulation of cell cycle Source: GO_Central
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process Source: GO_Central
Cellular Location
Z line
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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