Mouse Anti-FBXO15 Recombinant Antibody (CBXF-3303) (CBMAB-F0169-CQ)

This product is a mouse antibody that recognizes FBXO15. The antibody CBXF-3303 can be used for immunoassay techniques such as: ICFC.
See all FBXO15 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBXF-3303

Antibody Isotype

IgG2a

Application

ICFC

Basic Information

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, 5% trehalose

Concentration

0.2 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

F-box protein 15

Introduction

Members of the F-box protein family, such as FBXO15, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).

Entrez Gene ID

201456

UniProt ID

Q8NCQ5

Alternative Names

F-Box Protein 15; F-Box Only Protein 15; FBX15;

Research Area

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Cellular Location

Cytosol

References

Zhao, Y., Shim, N., Cui, Y. H., Kang, J. H., Yoo, K. C., Kim, S., ... & Lee, S. J. (2021). FBXO15 plays a critical suppressive functional role in regulation of breast cancer progression. Signal transduction and targeted therapy, 6(1), 1-4.

Zhang, Z., Wang, Y., Shan, Y., Zhou, R., & Yin, W. (2020). Oroxylin A alleviates immunoparalysis of CLP mice by degrading CHOP through interacting with FBXO15. Scientific reports, 10(1), 1-15.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Datasheet
SDS
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