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Mouse Anti-FCRL6 Recombinant Antibody (CBXF-2597) (CBMAB-F0173-CQ)

This product is a mouse antibody that recognizes FCRL6. The antibody CBXF-2597 can be used for immunoassay techniques such as: FC.
See all FCRL6 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXF-2597
Antibody Isotype
IgG1
Application
FC

Basic Information

Immunogen
CHO-derived recombinant human FCRL6/FcRH6, Lys16-Leu312, Accession # Q6DN72
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
A saline solution, BSA
Preservative
0.05% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Fc Receptor Like 6
Introduction
FCRL6 (Fc Receptor Like 6) is a Protein Coding gene. Diseases associated with FCRL6 include Viral Pneumonia and Dental Fluorosis. Gene Ontology (GO) annotations related to this gene include protein phosphatase binding. An important paralog of this gene is FCRL3.
Entrez Gene ID
343413
UniProt ID
Q6DN72
Alternative Names
Fc Receptor Like 6; Fc Receptor Homolog 6; FcR-Like Protein 6; FcRH6; IFGP6; IgSF Type I Transmembrane Receptor;
Research Area
Acts as a MHC class II receptor (PubMed:20519654).

When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8+ T cells (PubMed:17213291, PubMed:18991291).

Does not act as an Fc receptor (PubMed:18991291).
Biological Process
Cell surface receptor signaling pathway Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 20-307
Helical: 308-328
Cytoplasmic: 329-434
PTM
Phosphorylated on Tyr residues. Tyrosine phosphorylation induces association with phosphatase PTPN11, PTPN6, INPP5D, INPPL1 and GRB2.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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