Rabbit Anti-FOXN2 Recombinant Antibody (EG1234) (CBMAB-EN1491-LY)

Name: Rabbit Anti-FOXN2 Recombinant Antibody (EG1234)
SKU: CBMAB-EN1491-LY
Rating: 5 (1 reviews)

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Summary

Host Animal

Rabbit

Specificity

Human

Clone

EG1234

Antibody Isotype

IgG

Application

WB: 1:500~1:1000 ELISA: 1:20000

Basic Information

Immunogen

The antibody was produced against synthesized peptide derived from C-terminal of human FOXN2.

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

Forkhead Box N2

Introduction

This gene encodes a forkhead domain binding protein and may function in the transcriptional regulation of the human T-cell leukemia virus long terminal repeat. [provided by RefSeq, Jul 2008]

Entrez Gene ID

3344

UniProt ID

P32314

Alternative Names

Forkhead Box N2; Human T-Cell Leukemia Virus Enhancer Factor; HTLF; Forkhead Box Protein N2;

Function

Binds to the purine-rich region in HTLV-I LTR.

Biological Process

Regulation of transcription, DNA-templated Source: GO_Central
Skeletal muscle cell differentiation Source: Ensembl

Cellular Location

Nucleus

More Infomation

References

Jeong, S., Kim, S. A., & Ahn, S. G. (2022). HOXC6-Mediated miR-188-5p expression induces cell migration through the inhibition of the tumor suppressor FOXN2. International Journal of Molecular Sciences, 23(1), 9.

Liu, X. H., Liu, L. P., Xu, X. M., Hua, M., Kang, Q., Li, A., & Huang, L. (2021). FOXN2 suppresses the proliferation and invasion of human hepatocellular carcinoma cells. Eur. Rev. Med. Pharmacol. Sci, 25, 731-737.

Santibanez, B., Oliveira, S., Duggan, K., Lu, K., & Johnson, K. (2019). Abstract C49: Knockdown of FOXN2 enhances adhesion and reduces migration in pancreatic cancer cells. Cancer Research, 79(24_Supplement), C49-C49.

Dai, S. G., Guo, L. L., Xia, X., & Pan, Y. (2019). Long non-coding RNA WT1-AS inhibits cell aggressiveness via miR-203a-5p/FOXN2 axis and is associated with prognosis in cervical cancer. Eur Rev Med Pharmacol Sci, 23(2), 486-495.

Ye, H., & Duan, M. (2019). FOXN2 is downregulated in breast cancer and regulates migration, invasion, and epithelial–mesenchymal transition through regulation of SLUG. Cancer Management and Research, 11, 525.

Ma, J., Lu, Y., Zhang, S., Li, Y., Huang, J., Yin, Z., ... & Xu, S. (2018). β-Trcp ubiquitin ligase and RSK2 kinase-mediated degradation of FOXN2 promotes tumorigenesis and radioresistance in lung cancer. Cell Death & Differentiation, 25(8), 1473-1485.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Mouse Anti-FOXN2 Recombinant Antibody (CBXF-1786)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote
Second antibody and isotype control

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