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Mouse Anti-HTR3B Recombinant Antibody (CBT2511) (V2LY-0625-LY810)


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Tested Data
Mouse Anti-HTR3B Recombinant Antibody (CBT2511) (V2LY-0625-LY810) in ELISA
Mouse Anti-HTR3B Recombinant Antibody (CBT2511) (V2LY-0625-LY810) in ELISA
Mouse Anti-HTR3B Recombinant Antibody (CBT2511) (V2LY-0625-LY810) in WB
Mouse Anti-HTR3B Recombinant Antibody (CBT2511) (V2LY-0625-LY810) in WB
Mouse Anti-HTR3B Recombinant Antibody (CBT2511) (V2LY-0625-LY810) in WB
Mouse Anti-HTR3B Recombinant Antibody (CBT2511) (V2LY-0625-LY810) in WB
Mouse Anti-HTR3B Recombinant Antibody (CBT2511) (V2LY-0625-LY810) in WB
Mouse Anti-HTR3B Recombinant Antibody (CBT2511) (V2LY-0625-LY810) in WB
Mouse Anti-HTR3B Recombinant Antibody (CBT2511) (V2LY-0625-LY810) in IF
Mouse Anti-HTR3B Recombinant Antibody (CBT2511) (V2LY-0625-LY810) in IF
Mouse Anti-HTR3B Recombinant Antibody (CBT2511) (V2LY-0625-LY810) in FC
Mouse Anti-HTR3B Recombinant Antibody (CBT2511) (V2LY-0625-LY810) in FC

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT2511
Antibody Isotype
IgG2b
Application
WB, ICC, FC

Basic Information

Immunogen
Purified recombinant fragment of human HTR3B (AA: extra 23-150) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
ICC1:100-1:500
FC1:200-1:400
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Entrez Gene ID
9177
UniProt ID
O95264
Function
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.
Biological Process
Chemical synaptic transmission Source: GO_Central
Inorganic cation transmembrane transport Source: ComplexPortal
Ion transmembrane transport Source: GO_Central
Nervous system process Source: GO_Central
Regulation of membrane potential Source: GO_Central
Serotonin receptor signaling pathway Source: ComplexPortal
Signal transduction Source: GO_Central
Cellular Location
Cell membrane. Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.
Topology
Extracellular: 22-238
Helical: 239-259
Cytoplasmic: 260-268
Helical: 269-286
Extracellular: 287-303
Helical: 304-324
Cytoplasmic: 325-414
Helical: 415-435
Extracellular: 436-441
PTM
N-glycosylation required for membrane localization.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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