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Mouse Anti-IL13RA1 Recombinant Antibody (CBWJC-3805) (CBMAB-C5074WJ)

This product is a Mouse antibody that recognizes IL13RA1. This antibody CBWJC-3805 can be used for immunoassay techniques such as: ELISA, ICC, FC.
See all IL13RA1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJC-3805
Antibody Isotype
IgG1
Application
ELISA, ICC, FC

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Interleukin 13 Receptor Subunit Alpha 1
Introduction
The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq, Jul 2008]
Entrez Gene ID
3597
UniProt ID
P78552
Alternative Names
Interleukin 13 Receptor Subunit Alpha 1
Function
Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
Biological Process
Cell surface receptor signaling pathway Source: ProtInc
Cytokine-mediated signaling pathway Source: GO_Central
Oncostatin-M-mediated signaling pathway Source: GOC
Positive regulation of cell population proliferation Source: GO_Central
Cellular Location
Membrane
Topology
Extracellular: 22-343
Helical: 344-367
Cytoplasmic: 368-427
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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