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Mouse Anti-PCDH9 Recombinant Antibody (CBT2173) (V2LY-0625-LY685)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT2173
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Purified recombinant fragment of human PCDH9 (AA: 24-148) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Protocadherin 9
Entrez Gene ID
5101
UniProt ID
Q9HC56
Function
Potential calcium-dependent cell-adhesion protein.
Biological Process
Cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Homophilic cell adhesion via plasma membrane adhesion moleculesIEA:InterPro
Cellular Location
Cell membrane
Topology
Extracellular: 24-814
Helical: 815-835
Cytoplasmic: 836-1237
More Infomation

Zhang, Y., Zhu, Y., Chen, Y., Wang, Y., Liu, B., Pan, Y., ... & Yu, G. (2024). Nuclear translocation of cleaved PCDH9 impairs gastric cancer metastasis by downregulating CDH2 expression. Iscience, 27(2).

Xu, R., Liu, Z., Li, H., Luo, L., Zheng, Y., Mu, F., ... & Liu, Y. (2024). Influence of PCDH9 (rs9540720) and narcissistic personality traits on the incidence of major depressive disorder in Chinese first-year university students: findings from a 2-year cohort study. Frontiers in Genetics, 14, 1267972.

Zhang, J., Yang, H. Z., Liu, S., Islam, M. O., Zhu, Y., Wang, Z., & Chen, R. (2022). PCDH9 suppresses melanoma proliferation and cell migration. Frontiers in Oncology, 12, 903554.

Cai, G., Zou, R., Yang, H., Xie, J., Chen, X., Zheng, C., ... & Chen, R. (2022). Circ_0084043-miR-134-5p axis regulates PCDH9 to suppress melanoma. Frontiers in Oncology, 12, 891476.

Zhou, K., Wang, L., Sun, Z., Liu, Y., Zhu, Y., Liu, Z., ... & Shi, H. (2022). COP1 acts as a ubiquitin ligase for PCDH9 ubiquitination and degradation in human glioma. Molecular Neurobiology, 59(4), 2378-2388.

Wu, Q., Shi, X., Pan, Y., Liao, X., Xu, J., Gu, X., ... & Yu, G. (2022). The chemopreventive role of β-elemene in cholangiocarcinoma by restoring PCDH9 expression. Frontiers in Oncology, 12, 874457.

Zhang, L., Meng, X., Li, D., & Han, X. (2020). piR-001773 and piR-017184 promote prostate cancer progression by interacting with PCDH9. Cellular Signalling, 76, 109780.

Izycka, N., Sterzynska, K., Januchowski, R., & Nowak-Markwitz, E. (2019). Semaphorin 3A (SEMA3A), protocadherin 9 (PCdh9), and S100 calcium binding protein A3 (S100A3) as potential biomarkers of carcinogenesis and chemoresistance of different neoplasms, including ovarian cancer—Review of literature. Ginekologia polska, 90(4), 223-227.

Shi, C., Yang, Y., Zhang, L., Yu, J., Qin, S., Xu, H., & Gao, Y. (2019). MiR-200a-3p promoted the malignant behaviors of ovarian cancer cells through regulating PCDH9. OncoTargets and therapy, 8329-8338.

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For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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