Rabbit Anti-TREML2 Recombinant Antibody (CBYJT-4624) (CBMAB-T4153-YJ)

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Rabbit
Clone
CBYJT-4624
Application
ELISA
Immunogen
Recombinant Human TREML2 / TLT-2 protein
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Triggering Receptor Expressed On Myeloid Cells-Like 2
Introduction
TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 and TREM2, but it has distinct structural and functional properties (Allcock et al., 2003 [PubMed 12645956]).
Entrez Gene ID
UniProt ID
Alternative Names
Triggering Receptor Expressed On Myeloid Cells Like 2; Triggering Receptor Expressed On Myeloid Cells-Like Protein 2; C6orf76; TLT-2; TLT2; Triggering Receptor Expressed On Myeloid Cells-Like 2
Function
Cell surface receptor that may play a role in the innate and adaptive immune response. Acts as a counter-receptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation.
Biological Process
Biological Process T cell activation Source:UniProtKB1 Publication
Cellular Location
Cell membrane
Topology
Extracellular: 19-268
Helical: 269-289
Cytoplasmic: 290-321
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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