By Hallmark/Pathway

The progression from neoplastic transformation to metastatic dissemination is governed by the acquisition of specific biological capabilities—the hallmarks of cancer. These phenotypic alterations, ranging from sustained proliferative signaling to the evasion of immune destruction, are underpinned by profound dysregulation within intracellular kinase networks and transcriptional machinery. Contemporary research emphasizes the need to dissect these pathways not in isolation, but as integrated circuits that drive tumor heterogeneity and therapeutic resistance.

Targeting these mechanisms requires tools of exceptional specificity. Whether investigating the "angiogenic switch" mediated by hypoxic gradients or delineating the epithelial-mesenchymal transition (EMT) axis that facilitates invasion, the fidelity of molecular detection is paramount. Our portfolio is systematically organized to address these critical research nodes, offering validated antibodies and assays designed to interrogate cell cycle checkpoints, apoptotic thresholds, vascular remodeling, and the immunosuppressive tumor microenvironment with high-resolution precision.

Browse by Hallmark/Pathway

Select a pathway to explore targets, antibodies, and validation data.

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Target: CTLA4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: BN13
Application*: N, F, in vivo
In Vivo Assay Functional Assay
Target: PDCD1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: AG144
Application*: B, IH, In Vivo, WB
In Vivo Assay Functional Assay
Target: KDR
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: EG1209
Application*: ELISA, WB
Target: PDCD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: A1402
Application*: FC, IHC, IP, WB
Target: PECAM1
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: SZ31
Application*: IHC, WB
Target: PDCD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: EH12.2H7
Application*: FC
Target: PECAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: PECAM-1
Application*: WB, P
Target: PECAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: BV8
Application*: E, IP, F
Target: PECAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2363
Application*: WB, IP, IC
Target: PECAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MEM-05
Application*: F
Target: PECAM1
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0922
Application*: F
Target: PECAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CLB-HEC/75
Application*: F, FN, IF
Target: TIGIT
Host: Mouse
Antibody Isotype: IgG3
Specificity: Human
Clone: CBYJT-3140
Application*: F
Target: CD68
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 039
Application*: E
Target: PECAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4D1
Application*: WB, P
Target: PECAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: 3H1221
Application*: F, IP
Target: PECAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2H8G4F10
Application*: WB, P
Target: KDR
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: CBYY-1125
Application*: E, WB
Target: KDR
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYY-1098
Application*: WB, IH, IP
Target: KDR
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: D5B1
Application*: WB, IP, P, IF, F
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