ADD1

Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. [provided by RefSeq, Aug 2017]
Full Name
Adducin 1
Function
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.
Biological Process
Actin cytoskeleton organization
Actin filament bundle assembly
Barbed-end actin filament capping
Cell morphogenesis
Cellular response to calcium ion
Cell volume homeostasis
Erythrocyte differentiation
Hemoglobin metabolic process
Homeostasis of number of cells within a tissue
In utero embryonic development
IRE1-mediated unfolded protein response
Multicellular organism growth
Positive regulation of adherens junction organization
Positive regulation of establishment of endothelial barrier
Positive regulation of protein binding
Transmembrane transport
Cellular Location
Cell membrane; Cytoskeleton
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Anti-ADD1 antibodies

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Rabbit Anti-ADD1 Recombinant Antibody (V2-179872) (CBMAB-A1252-YC)

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Target: ADD1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey
Clone: V2-179872
Application*: WB, IP
Datasheet SDS

Mouse Anti-ADD1 Recombinant Antibody (V2-179871) (CBMAB-A1250-YC)

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Target: ADD1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: V2-179871
Application*: E, IH, WB
Datasheet SDS

Mouse Anti-ADD1 Recombinant Antibody (CBT2090) (V2LY-0625-LY243)

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Target: ADD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2090
Application*: IH
Datasheet SDS

ADD1 Matched Antibody Pair (025) (APMAB-025LY)

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Target: ADD1
Specificity: Human
Datasheet SDS

Mouse Anti-ADD1 Recombinant Antibody (V2-12523) (CBMAB-1013-CN)

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Target: ADD1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: V2-12523
Application*: WB, E, F, IH, MC, IC
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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