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ADD1 Matched Antibody Pair (025) (APMAB-025LY)

This antibody pair set can be used for detecting and quantifying protein level of human ADD1.
See all ADD1 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-ADD1 polyclonal antibody, 100 ug
Detection Antibody
Anti-ADD1 Mouse monoclonal, IgG1 antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. [provided by RefSeq, Aug 2017]
Alternative Names
Adducin 1; Adducin 1 (Alpha); Alpha-Adducin; ADDA; Erythrocyte Adducin Alpha Subunit; Erythrocyte Adducin Subunit Alpha;
Entrez Gene ID
118
UniProt ID
P35611

Yermolenko, S., Chumachenko, Y., Orlovskyi, V., Moiseyenko, I., & Orlovskyi, O. (2021). The Association between Gly460Trp-Polymorphism of Alpha-Adducin 1 Gene (ADD1) and Arterial Hypertension Development in Ukrainian Population. International Journal of Hypertension, 2021.

Su, C. Y., Yan, R. L., Hsu, W. H., Chu, C. T., Chang, H. C., Lai, C. C., ... & Chen, H. C. (2019). Phosphorylation of adducin-1 by cyclin-dependent kinase 5 is important for epidermal growth factor-induced cell migration. Scientific reports, 9(1), 1-11.

Gupta, S., Jhawat, V., Agarwal, B. K., Roy, P., & Saini, V. (2019). Alpha adducin (ADD1) gene polymorphism and new onset of diabetes under the influence of selective antihypertensive therapy in essential hypertension. Current hypertension reviews, 15(2), 123-134.

Hsu, W. H., Wang, W. J., Lin, W. Y., Huang, Y. M., Lai, C. C., Liao, J. C., & Chen, H. C. (2018). Adducin‐1 is essential for spindle pole integrity through its interaction with TPX2. EMBO reports, 19(8), e45607.

Park, M. Y., & Lee, M. S. (2018). Effects of Sodium Intake on the Association between the Salt-Sensitive Gene, Alpha-Adducin 1 (ADD1), and Inflammatory Cytokines in the Prevalence of Children Obesity. Journal of Lipid and Atherosclerosis, 7(2), 98-109.

Bayoumy, N. M., El-Shabrawi, M. M., Leheta, O. F., & Omar, H. H. (2017). α-Adducin gene promoter DNA methylation and the risk of essential hypertension. Clinical and Experimental Hypertension, 39(8), 764-768.

Luo, C., & Shen, J. (2017). Adducin in tumorigenesis and metastasis. Oncotarget, 8(29), 48453.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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