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ANXA4

Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2016]
Full Name
Annexin A4
Function
Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.
Biological Process
Epithelial cell differentiation Source: UniProtKB
Negative regulation of apoptotic process Source: UniProtKB
Negative regulation of interleukin-8 production Source: BHF-UCL
Negative regulation of NF-kappaB transcription factor activity Source: BHF-UCL
Notch signaling pathway Source: Ensembl
Regulation of transcription by RNA polymerase II Source: BHF-UCL
Signal transduction Source: UniProtKB
Cellular Location
Extracellular exosome; Nuclear membrane; Nucleus; Plasma membrane; Cell surface; Collagen-containing extracellular matrix; Cytoplasm; Perinuclear region of cytoplasm; Vesicle membrane
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Anti-ANXA4 antibodies

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Mouse Anti-ANXA4 Recombinant Antibody (CBYC-A631) (CBMAB-A2923-YC)

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Target: ANXA4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBYC-A631
Application*: E, WB, P, IF, IP
Datasheet SDS

Mouse Anti-ANXA4 Recombinant Antibody (1D3) (CBMAB-A2922-YC)

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Target: ANXA4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1D3
Application*: E, P, WB
Datasheet SDS

Mouse Anti-ANXA4 Recombinant Antibody (A2921) (CBMAB-A2921-YC)

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Target: ANXA4
Host: Mouse
Antibody Isotype: IgG2c
Specificity: Human
Clone: A2921
Application*: WB, IH, IF
Datasheet SDS

Mouse Anti-ANXA4 Recombinant Antibody (H2) (CBMAB-A2920-YC)

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Target: ANXA4
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: H2
Application*: E, WB, IF, IP
Datasheet SDS

Rabbit Anti-ANXA4 Antibody (JG37-83) (CBMAB-1015CQ)

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Target: ANXA4
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: JG37-83
Application*: FC, WB, IF, P
Datasheet SDS

ANXA4 Matched Antibody Pair (081) (APMAB-081LY)

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Target: ANXA4
Specificity: Human
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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