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ANXA4 Matched Antibody Pair (081) (APMAB-081LY)

This antibody pair set can be used for detecting and quantifying protein level of human ANXA4.
See all ANXA4 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-ANXA4 polyclonal antibody, 100 ug
Detection Antibody
Anti-ANXA4 Mouse polyclonal antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2016]
Alternative Names
Annexin A4; Carbohydrate-Binding Protein P33/P41; Placental Anticoagulant Protein II; 35-Beta Calcimedin; Chromobindin-4; Lipocortin IV; Endonexin I; Protein II; Annexin-4; PAP-II; P32.5;
Entrez Gene ID
307
UniProt ID
P09525

Li, N., Xi, Y., Du, H., Zhou, H., & Xu, Z. (2021). Annexin A4 is dispensable for hair cell development and function. Frontiers in cell and developmental biology, 9.

Florentsen, C. D., Kamp-Sonne, A., Moreno-Pescador, G., Pezeshkian, W., Zanjani, A. A. H., Khandelia, H., ... & Bendix, P. M. (2021). Annexin A4 trimers are recruited by high membrane curvatures in Giant Plasma Membrane Vesicles. Soft Matter, 17(2), 308-318.

Peng, Y., Zhang, Z., Zhang, A., Liu, C., Sun, Y., Peng, Z., & Liu, Y. (2021). Membrane-cytoplasm translocation of annexin A4 is involved in the metastasis of colorectal carcinoma. Aging (Albany NY), 13(7), 10312.

Mularski, A., Sønder, S. L., Heitmann, A. S. B., Nylandsted, J., & Simonsen, A. C. (2021). Simultaneous membrane binding of Annexin A4 and A5 suppresses 2D lattice formation while maintaining curvature induction. Journal of Colloid and Interface Science, 600, 854-864.

Saad, Z. M., Fouad, Y., Ali, L. H., & Hassanin, T. M. (2020). Clinical Significance of Annexin A4 as a Biomarker in the Early Diagnosis of Hepatocellular Carcinoma. Asian Pacific Journal of Cancer Prevention: APJCP, 21(9), 2661.

Heinick, A., Pluteanu, F., Hermes, C., Klemme, A., Domnik, M., Husser, X., ... & Müller, F. U. (2020). Annexin A4 N‐terminal peptide inhibits adenylyl cyclase 5 and limits β‐adrenoceptor‐mediated prolongation of cardiac action potential. The FASEB Journal, 34(8), 10489-10504.

Nakayama, M., Miyagawa, H., Kuranami, Y., Tsunooka‐Ota, M., Yamaguchi, Y., & Kojima‐Aikawa, K. (2020). Annexin A4 inhibits sulfatide‐induced activation of coagulation factor XII. Journal of Thrombosis and Haemostasis, 18(6), 1357-1369.

Xu, Y., Sui, L., Qiu, B., Yin, X., Liu, J., & Zhang, X. (2019). ANXA4 promotes trophoblast invasion via the PI3K/Akt/eNOS pathway in preeclampsia. American Journal of Physiology-Cell Physiology, 316(4), C481-C491.

Zheng, M. D., Wang, N. D., Li, X. L., Yan, J., Tang, J. H., Zhao, X. H., & Zhang, Z. (2018). Toosendanin mediates cisplatin sensitization through targeting Annexin A4/ATP7A in non-small cell lung cancer cells. Journal of natural medicines, 72(3), 724-733.

Boye, T. L., Maeda, K., Pezeshkian, W., Sønder, S. L., Haeger, S. C., Gerke, V., ... & Nylandsted, J. (2017). Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair. Nature communications, 8(1), 1-11.

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For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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